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You regularly get entangled in discussions about science and religion. You might have also created quite a few publications on the topic. Don’t you feel that at some point We're going to know every little thing Which God’s part are going to be in excess of?

[Laughs] ‘It absolutely was definitely a great risk! At the time, I had been very well informed that it could go Mistaken and that I could grow to be much less effective, but I just disregarded that. Curiosity has normally been my strongest driving pressure. And fortuitously it all labored out.’

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

2010, made a new way (‘wedging transfer’) to manipulate nanostructures; initially report of DNA translocation as a result of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into solid-point out nanopores

SMC complexes can go Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion

We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this assess the elemental job of spatial confinement at the molecular and mobile amount. Our jobs involve the subsequent:

Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

The rotors harness Vitality from a nanoscale drinking water and ion movement that is created by a static chemical or electrochemical prospective gradient within the nanopore, which are recognized through a salt gradient or used voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological conditions, suggesting solutions to constructing Vitality-transducing motors at nanoscale interfaces.

Bulk-surface area coupling identifies the mechanistic connection involving Min-protein styles in vivo and in vitro

Testing pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments

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Illustration (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in red, and also a 3D https://www.ceesdekker.net rendering from the movement of the DNA rod is shown.